Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning
✍ Scribed by Zrinka Kovarik; Maja Čalić; Goran Šinko; Anita Bosak; Suzana Berend; Ana Lucić Vrdoljak; Božica Radić
- Book ID
- 113517674
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 407 KB
- Volume
- 175
- Category
- Article
- ISSN
- 0009-2797
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📜 SIMILAR VOLUMES
The bispyridinium oxime HI-6, 1-((((4-amino-carbonyl)pyridinio)methoxy) methyl)-2-(hydroxyimino)methyl)pyridinium dichloride monohydrate, combined with atropine is an effective treatment for soman (pinacolyl methylphosphonofluoridate) poisoning but is relatively ineffective against tabun (ethyl N-di
## Abstract The influence of the combination of oximes on the reactivating and therapeutic efficacy of antidotal treament of acute tabun poisoning was evaluated. The ability of two combinations of oximes (HI‐6 + obidoxime and HI‐6 + K203) to reactivate tabun‐inhibited acetylcholinesterase and reduc