## Abstract The reaction kinetics of 2‐bromo‐5‐nitro thiophene with piperidine was studied in a solvent with a mixture of propan‐2‐ol with methanol and __n__‐hexane at 25°C. The measured rate coefficients of the reaction demonstrated dramatic variations in propan‐2‐ol–__n__‐hexane mixtures and mild
Oximes as products in the reactions of 5-substituted 2-nitrothiophenes with arylacetonitriles
✍ Scribed by Nazar I. Rad; Yuriy O. Teslenko; Mykola D. Obushak; Vasyl S. Matiychuk; Roman Z. Lytvyn
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 76 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.723
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✦ Synopsis
Abstract
It has been shown that reactions 5‐substituted 2‐nitrothiophenes with arylacetonitriles in the presence of potassium hydroxide in methanol lead to the formation of the new 2‐(hydroxyimino)‐5‐R‐3(2H)‐thienylideneacetonitriles. Under proposed reaction conditions, the formation of thieno[2,3‐c]isoxazole was not the case. J. Heterocyclic Chem., (2011).
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract It has been shown that reactions of 4‐nitroimidazoles and some other nitroaromatic systems with phenyl‐acetonitrile in the presence of sodium methoxide in methanol lead to the reduction of the nitro to nitroso group and to the nucleophilic displacement of hydrogen atom at the ring by th