✦ LIBER ✦
Oxime esters of anthraquinone as photo-induced DNA-cleaving agents for single- and double-strand scissions
✍ Scribed by Jih Ru Hwu; Shwu-Chen Tsay; Shih Chin Hong; Yi-Jing Leu; Chih-Fen Liu; Shang-Shing P Chou
- Book ID
- 104253252
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 133 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Anthraquinone-O-9-(4-cyanobenzoyl)oxime (13) with binding constant of 4.49×10 4 M -1 exhibited single-strand scission of DNA at the concentration of 10 mM and double-strand scission at 50 mM upon UV irradiation.