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Oxidizing species in the mechanism of cytochrome P450

✍ Scribed by Ortiz de Montellano, Paul R.; De Voss, James J.


Book ID
120979516
Publisher
Royal Society of Chemistry
Year
2002
Tongue
English
Weight
394 KB
Volume
19
Category
Article
ISSN
0265-0568

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## Abstract Cytochrome P450 (P450) enzymes catalyze a variety of oxidation and some reduction reactions, collectively involving thousands of substrates. A general chemical mechanism can be used to rationalize most of the oxidations and involves a perfenyl intermediate (FeO^3+^) and odd‐electron che