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Oxidized glucocorticoids counteract glucocorticoid-induced apoptosis in murine thymocytes in vitro

✍ Scribed by Toshihiko Hirano; Hiroshi Horigome; Hiroyuki Ishishita; Sayaka Uda; Kitaro Oka


Book ID
117172935
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
385 KB
Volume
68
Category
Article
ISSN
0024-3205

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## Abstract Apoptosis can be induced in primary cultures of mouse thymocytes using the glucocorticoid dexamethasone. Addition of the polyamine spermine simultaneously with dexamethasone reduces the induction of apoptosis compared to treatment with dexamethasone alone. We investigated the signal tra