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Oxidative stress interference with the nuclear factor- κB activation pathways

✍ Scribed by Sonia Schoonbroodt; Jacques Piette

Book ID
113992355
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
682 KB
Volume
60
Category
Article
ISSN
0006-2952

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✍ Andrew Bowie; Luke A.J O’Neill 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 458 KB

Nuclear factor-kappaB (NFKB) is a transcription factor with a pivotal role in inducing genes involved in physiological processes as well as in the response to injury and infection. A model has been proposed whereby the diverse agents that activate NFkappaB do so by increasing oxidative stress within