✦ LIBER ✦

Oxidative stress and the development of diabetic complications - antioxidants and lipid peroxidation in erythrocytes and cell membrane.

✍ Scribed by Anusha Parthiban; Selvamani Vijayalingam; K.Radha Shanmugasundaram; Rema Mohan

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 264 KB
Volume: 19
Category: Article
ISSN: 1065-6995
DOI: 10.1006/cbir.1995.1040

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Erythrocytes isolated from 131 cases of Non‐Insulin Dependent Diabetes Mellitus (NIDDM) were studied for lipid peroxidation, antioxidant defences, and the maximum peroxidisable substrate in the cell membrane. Antioxidant defences are lowered in NIDDM, followed by significant rise in lipid peroxidation products. However, in the erythrocyte membrane, the total polyunsaturated peroxidisable lipids are lower than in normal erythrocytes which may be a causative factor affecting the survival of the cells.

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