Oxidative stress and diabetic neuropathy: pathophysiological mechanisms and treatment perspectives
โ Scribed by P. Sytze van Dam
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 128 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1520-7552
- DOI
- 10.1002/dmrr.287
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The scope of the present review is to describe epidemiology, classification, symptomatology and treatment of diabetic peripheral somatic neuropathy and autonomic neuropathy. Special attention is paid to the use of local anaesthetic agents in painful diabetic neuropathy. Denervation hypersensitivity
## Abstract Free radicals and oxidative stress have been implicated in the etiology of diabetes and its complications. This in vivo study has examined whether subacute administration of pycnogenol, a French pine bark extract containing procyanidins that have strong antioxidant potential, alters bio