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Oxidative Stress and Cyclooxygenase-2 Induction Mediate Cyanide-Induced Apoptosis of Cortical Cells

โœ Scribed by L. Li; K. Prabhakaran; Y. Shou; J.L. Borowitz; G.E. Isom


Book ID
112268683
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
409 KB
Volume
185
Category
Article
ISSN
0041-008X

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The mechanisms involved in the anti-carcinogenic activity of selenium remain to be elucidated. In the present study, we examined sodium selenite-induced oxidative stress and apoptosis in a human hepatoma cell line (HepG 2 ). Sodium selenite (10 M) exerted clear cytotoxic effect, as shown by the sign