Oxidative rearrangement of alkynes to carboxylic acid esters by [Hydroxy(tosyloxy)iodo]benzene in methanol

✍ Scribed by Robert M Moriarty; Radhe K Vaid; Michael P Duncan; Beena K Vaid

• Publisher: Elsevier Science
• Year: 1987
• Tongue: French
• Weight: 187 KB
• Volume: 28
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)96224-5

✦ Synopsis

A direct synthesis of methyl aryl alkanoate via oxidative rearrangement of a ynes using [hydroxy(tosyloxy)iodo]benzene in methanol T-described.

Recently attention has been directed towards the synthesis of arylalkanoic acids as anti-inflammatory agentsI12.

As part of our studies on synthetic uses of hypervalent iodine,3 we became interested in the synthesis of arylalkanoic acids using this