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Oxidative reactivity of the tryptophan metabolites 3-hydroxyanthranilate, cinnabarinate, quinolinate and picolinate

✍ Scribed by James A. Dykens; Stephen Gene Sullivan; Arnold Stern

Book ID
115780012
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
930 KB
Volume
36
Category
Article
ISSN
0006-2952

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## Abstract 3‐Hydroxyanthranilic acid (3HAA) is one of the tryptophan metabolites along the kynurenine pathway and induces apoptosis in T cells. We investigated the mechanism of 3HAA‐induced apoptosis in mouse thymocytes. The optimal concentration of 3HAA for apoptosis induction was 300–500 Β΅M. The