Oxidative reactions of the pentose pathway and the origin of reducing equivalents for the biosynthesis of rubber in Hevea brasiliensis latex

✍ Scribed by Barbarín Arreguín; Roberto Arreguín-Espinosa

• Publisher: Wiley (John Wiley & Sons)
• Year: 2000
• Tongue: English
• Weight: 85 KB
• Volume: 75
• Category: Article
• ISSN: 0268-2575
• DOI: 10.1002/(sici)1097-4660(200004)75:4<294::aid-jctb209>3.0.co;2-4

✦ Synopsis

The presence of the oxidative reactions of the pentose phosphate pathway in hevea latex and their interaction with the biosynthesis of rubber are demonstrated using radioisotopes. During the second oxidation±reduction reaction of the pentose phosphate pathway the tritium in C 3 of glucose-6phosphate is transported as tritiated nicotinamide adenine dinucleotide phosphate and serves to reduce [3-14 C] 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate. Reduced nicotinamide adenine dinucleotide phosphate is the inter-connection between these two metabolic routes present in hevea latex, thus the hydrogens of glucose end up in rubber.