Oxidative Radical Cyclizations onto Imidazoles and Pyrroles Using Bu 3 SnH. -The title reaction yields [1,2-c]-fused imidazoles or [1,2-c]-fused pyrroles via cyclization of a nucleophilic N-alkyl radical onto the heterocyclic ring followed by oxidative rearomatization. -(ALDABBAGH, F.;
Oxidative radical cyclisations onto imidazoles and pyrroles using Bu3SnH
β Scribed by Fawaz Aldabbagh; W.Russell Bowman; Emma Mann
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 254 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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## Abstract For Abstract see ChemInform Abstract in Full Text.
Efficient 5-endo and 6-endo oxidative radical cyclizations on enamide systems are described using nBu 3 SnH and dilauroyl peroxide both as initiator and oxidant. Dibenzoyl peroxide and dicumyl peroxide were also tested in the same reaction and the product yields were very similar to those obtained w
Reactions between the Co(I) species derived from cobalt(II1) 'salen'( and (e-ally11 or (g-but-3-enyl) iodophenol, leads to isolatable cobalt complexes, viz (2), ( 13), which can be converted into substituted benzofurans, i.e. (S), ( 6) and benzopyrans, i.e. ( 14), ( 15); similarly interaction betwe