Oxidative polymorphism of debrisoquine i
✍
J. M. Ladero; J. Benítez; J. F. González; E. Vargas; M. Díaz-Rubio
📂
Article
📅
1991
🏛
Springer
🌐
English
⚖ 343 KB
The oxidative polymorphism of debrisoquine (DBQ) has been determined in 89 patients with colo-rectal cancer and in 556 normal control subjects. Four patients and 34 controls, with a metabolic ratio greater than 12.6, were classified as poor metabolisers of DBQ (n.s.). No difference was found in the