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Oxidative Metabolism of Pyruvate Is Required for Meiotic Maturation of Murine Oocytes In Vivo

✍ Scribed by Johnson, M. T.; Freeman, E. A.; Gardner, D. K.; Hunt, P. A.

Book ID
120292397
Publisher
Society for the Study of Reproduction
Year
2007
Tongue
English
Weight
277 KB
Volume
77
Category
Article
ISSN
0006-3363

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This study was conducted to determine whether endothelial-derived nitric oxide synthase (eNOS) affects meiotic maturation of mouse oocytes in vitro. Cumulus-oocyte complexes (COC) were isolated from ovarian follicles of 27-day-old PMSGprimed wildtype (WT), and eNOS-knockout (eNOS-KO) females, and cu