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Oxidative Footprinting of Fibrillar and Prefibrillar Oligomer Forms of Amyloid Beta

✍ Scribed by Klinger, Alexandra L.; Axelsen, Paul H.


Book ID
123285403
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
38 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract Both soluble and membrane‐bound prefibrillar assemblies of Abeta (AΞ²) peptides have been associated with Alzheimer's disease (AD). The size and nature of these assemblies vary greatly and are affected by many factors. Here, we present models of soluble hexameric assemblies of AΞ²42 and s