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Oxidative Folding and N-Terminal Cyclization of Onconase †

✍ Scribed by Welker, Ervin; Hathaway, Laura; Xu, Guoqiang; Narayan, Mahesh; Pradeep, Lovy; Shin, Hang-Cheol; Scheraga, Harold A.


Book ID
127317532
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
150 KB
Volume
46
Category
Article
ISSN
0006-2960

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## Abstract Small disulfide‐rich peptides are translated as larger precursors typically containing an N‐terminal prepro sequence. In this study, we investigated the role of a propeptide in the oxidative folding of an extremely hydrophobic δ‐conotoxin, PVIA. δ‐Conotoxin PVIA (δ‐PVIA) is a 29‐amino a