Oxidative fluorination of trialkyl phosphites using 2-hydroperfluoropropyl azide
β Scribed by S. A. Lermontov; A. V. Popov; I. I. Sukhozhenko; I. V. Martynov
- Book ID
- 112444954
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 49 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1573-9171
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## Abstract 2βHydroperfluoropropyl azide CF~3~CHFCF~2~N~3~, 1, an inexpensive, readily available, and stable (easy to store) compound, is suggested as an effective fluorinating reagent for different classes of trivalent organophosphorus compounds in accordance with the general scheme R~3~P β R~3~PF
An experimentally easy method for reqio-and stereospecific introduction of isotopic (I80 or 170) oxyqen into phosphorus di-and triesters of bioloqical interest is described and applied to 'DO-labelinq of cTMP's. Nucleoside 3',5'-cyclic monophosphates stereospecifically labeled with I80 or I70 in the