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OXIDATIVE ENZYMES AND PHOSPHORYLASE IN CENTRAL-CORE DISEASE OF MUSCLE

✍ Scribed by Dubowitz, Victor; Everson Pearse, A.G.


Book ID
122798767
Publisher
The Lancet
Year
1960
Tongue
English
Weight
674 KB
Volume
276
Category
Article
ISSN
0140-6736

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Impairment of muscle glycogenolysis in McArdle's disease (myophosphorylase deficiency) leads to exercise intolerance and exercise-induced myalgia. The pathophysiology of these symptoms is not entirely clear. We used phosphorus magnetic resonance spectroscopy to measure muscle phosphate metabolite co