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Oxidative DNA Damage Induced by Equine Estrogen Metabolites: Role of Estrogen Receptor α

✍ Scribed by Liu, Xuemei; Yao, Jiaqin; Pisha, Emily; Yang, Yanan; Hua, Yousheng; van Breemen, Richard B.; Bolton, Judy L.

Book ID
127053463
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
92 KB
Volume
15
Category
Article
ISSN
0893-228X

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## Abstract Reactive oxygen species (ROS) are produced by a wide variety of exogenous chemicals and metabolic processes and cause a broad spectrum of damage to biological systems. As a consequence, ROS react with DNA, among many other biological targets, disrupting its structure and functionality.