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Oxidative DNA damage following exposure to dimethylarsinous iodide: the formation of cis-thymine glycol

✍ Scribed by Kenzo Yamanaka; Mutsumi Mizoi; Mariko Tachikawa; Akira Hasegawa; Mikio Hoshino; Shoji Okada


Book ID
119537655
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
273 KB
Volume
143
Category
Article
ISSN
0378-4274

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✍ S.P. Markey; C.J. Markey; Wang T.-C.L.; RodrΓ­guez J.B. πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 750 KB

A technique for the measurement of thymine glycol at parts per million concentrations in double-stranded polymeric DNA is described. The procedure utilizes base to ring-open DNA-bound thymine glycol in the presence of monomeric [(2)H4]thymine glycol as an internal standard, followed by reduction, so