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Oxidative damage to purines in DNA: Role of mammalian Ogg1

✍ Scribed by Arne Klungland; Svein Bjelland

Book ID
113567796
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
760 KB
Volume
6
Category
Article
ISSN
1568-7864

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✍ Fabio Farinati; Romilda Cardin; Marina Bortolami; Donato Nitti; Daniela Basso; M πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 103 KB πŸ‘ 1 views

## Abstract Oxidative DNA damage is thought to play an important part in the pathogenesis of __H. pylori__‐induced mucosal damage. 8‐OHdG is a sensitive marker of DNA oxidation and is repaired by a polymorphic glycosylase (__OGG1__) more effectively than by __OGG1__‐Cys^326^. The aims of this study