𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis

✍ Scribed by Fengmin Lu; Mary Selak; John O’Connor; Sidney Croul; Carlos Lorenzana; Catalin Butunoi; Bernadette Kalman

Book ID
119465168
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
553 KB
Volume
177
Category
Article
ISSN
0022-510X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Decreased antioxidant enzyme activity an
Decreased antioxidant enzyme activity and increased mitochondrial DNA damage in cellular models of Machado-Joseph disease
✍ Ya-Chun Yu; Chen-Ling Kuo; Wen-Ling Cheng; Chin-San Liu; Mingli Hsieh 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB

## Abstract Machado‐Joseph disease (MJD)/spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by polyglutamine expansion in the ataxin‐3 protein that confers a toxic gain of function. Because of the late onset of the disease, we hypothesize that the accumu