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Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age

✍ Scribed by Hafiz Mohmmad Abdul; Rukhsana Sultana; Daret K. St. Clair; William R. Markesbery; D. Allan Butterfield

Book ID
113630670
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
394 KB
Volume
45
Category
Article
ISSN
0891-5849

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## Abstract Alzheimer's disease (AD) is the most prevalent form of dementia among the elderly. Although the underlying cause has yet to be established, numerous data have shown that oxidative stress is implicated in AD as well as in preclinical stages of AD, such as mild cognitive impairment (MCI).