Oxidative Cleavage of the CarbonCarbon σ-Bond Using Reusable Copper on Iron

✍ Scribed by Ren-Jie Song; Yu Liu; Rui-Xiang Hu; Yan-Yun Liu; Ji-Cheng Wu; Xu-Heng Yang; Jin-Heng Li

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 267 KB
• Volume: 353
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.201100225

✦ Synopsis

An efficient and resuble copper on iron catalyst has been prepared for the cleavage of the carbon-carbon s-bond in a-aminocarbonyl compounds leading to the corresponding formylamides and acids with a maximal TON of up to 51,000. It is noteworthy that the copper on iron catalyst can be easily separated from the reaction mixture, and retains its activity after several reuses.