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Oxidative and synthetic functions of n-butyrate in colonocytes

✍ Scribed by W. E. W. Roediger; François Guillemot; Christelle Neut; Jean-Frédéric Colombel; Antoine Cortot

Book ID
112678044
Publisher
Springer
Year
1992
Tongue
English
Weight
336 KB
Volume
35
Category
Article
ISSN
0012-3706

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## Background: The combination of fish oil-derived docosahexaenoic acid (dha) (22:6; omega 3 [n-3]) and butyrate (4:0), a fiber fermentation product, synergized to enhance colonocyte apoptosis by inducing a p53-independent, oxidation sensitive, mitochondrial ca(2+) -dependent (intrinsic) pathway.