An improved procedure for regiospecific 0-alkylation of b-tetronic acids with primary and secondary alcohols, based upon Mitsunobu conditions, is presented. The reaction conditions are very mild and compatible with a variety of hydroxyl protecting groups such as MOM, t-BuMezSi, isopropylidine and es
Oxidations of some α-amino acids under mitsunobu reaction conditions
✍ Scribed by Teodozyj Kolasa; Marvin J. Miller
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 258 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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## Abstract For Abstract see ChemInform Abstract in Full Text.
2-Methoxyethanol chemical ionization of amines, carboxylic acids and amino acids has been found to produce numerous adduct ions. The most intense adduct ions for amines are [M H] and [M 77] , for carboxylic acids [M 27] , [M 59] and [M 77] , and for amino acids [M H] , [M 13] , [M 27] and [M 77] . E