A quantitative structure–activity relati
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David F. V. Lewis; Craig Sams; George D. Loizou
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Article
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2003
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John Wiley and Sons
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English
⚖ 84 KB
## Abstract The results of quantitative structure–activity relationships for eight alkyl benzenes undergoing oxidative metabolism via human CYP2E1 are reported. Molecular orbital calculations via the AM1 method were employed for the generation of electronic structural descriptors against experiment