Oxidation of primary alcohols to carboxylic acids made easy at iridium
β Scribed by Bianchini, Claudio; Meli, Andrea; Peruzzini, Maurizio; Vizza, Francesco
- Book ID
- 120996794
- Publisher
- American Chemical Society
- Year
- 1990
- Tongue
- English
- Weight
- 386 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
As the second volume in a comprehensive encyclopedia of organic reactions, this work provides an elaborated description of the experimental methods used for the oxidation of alcohols to acids. It supplies important data on possible interferences from protecting groups and functional groups, as well
A novel CrO~ catalyzed oxidation of primary alcohols to the carboxylic acids is reported. The oxidation proceeds smoothly with only 1-2 tool % of CrO 3 and 2.5 equivalents of H~IO 6 in wet MeCN to give the carboxylic acids in excellent yield. No significant racemization is observed for alcohols with