Oxidation of N-(4-Chlorophenyl)-N′-hydroxyguanidine to N-(4-Chlorophenyl)urea and Nitric Oxide by Photoexcited Iron Porphyrins
✍ Scribed by Andrea Maldotti; Alessandra Molinari; Irene Vitali; Elena Ganzaroli; Pierrette Battioni; Delphine Mathieu; Daniel Mansuy
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 184 KB
- Volume
- 2004
- Category
- Article
- ISSN
- 1434-1948
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The addition of Grignard reagents to D-erythro-4-pentenose N-benzyl nitrone 5, which is easily accessible from D-ribose, furnishes ω-unsaturated hydroxylamines that readily undergo Cope-House cyclization to afford pyrrolidine N-oxides. The stereoselectivity of the addition step is altered by either