Oxidation of Isatins to Isatoic Anhydrides and 2,3-Dioxo-1,4-benzoxazines
✍ Scribed by Dr. Gernot Reissenweber; Dr. Dietrich Mangold
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 211 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract magnified image The Lewis acid catalyzed synthesis and chromatographic purification of isatoic anhydride‐derived 2‐(2′‐anilinyl)‐1,3‐benzoxazole (**2**) can result in the co‐isolation of **2** and a light pink colored impurity (<5%). This latter species has been identified (NMR, single
## Abstract Substituted 2‐(benzylamino)‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2‐Bromo‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones show similar degradation under alkaline conditions, while replacement of Br at C