✦ LIBER ✦
Oxidation of cystine to cysteic acid by bromine in 18O-labelled water, evidence for a cyclic carboxylic-sulfenic anhydride
✍ Scribed by Robert H. White
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- French
- Weight
- 281 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Oxidation by bromine of L-fgstine dissolved in acidified 180-enriched water (95 atom X cysteic acid which copbained t w ; l 8 0 atoms in the carboxylic acid portion and two of the mo&cule.
It is postulated that the incorporation of a single intramolecular transfer of a carboxyl oxygen via a cyclic carboxylic-sulfenic anhydride intermediate which is formed during the oxidation. postulated to exchange from either the cyclic anhydride or the free carboxylic acid during the reaction. led to the production of 0 atoms in the sulfonic acid portion 0 into the sulfonic acid results from an
The remaining carboxyl oxygen is