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Oxidation of anthracycline anticancer agents by the peroxidase mimic microperoxidase 11 and hydrogen peroxide

โœ Scribed by Krzysztof J. Reszka; Michael L. McCormick; Bradley E. Britigan


Book ID
114275583
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
375 KB
Volume
35
Category
Article
ISSN
0891-5849

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Snmmary : Heme-undecapeptide, microperoxidase-11, prepared from cyto&rome c by pepsin digestion, retains the proximal 6th His-18 ligand. Microperoxidase is thought to be a unique peroxidase which does not have a substrate binding site. Compared with hemin-Cl, microperoxidase-11 was an effective cat