Oxidation of 7-Deazaguanine by One-Electron and Oxo-Transfer Oxidants: Mismatch-Dependent Electrochemistry and Selective Strand Scission

Oxidation of 9-β-d-ribofuranosyl uric ac

Oxidation of 9-β-d-ribofuranosyl uric acid by one-electron oxidants versus singlet oxygen and its implications for the oxidation of 8-oxo-7,8-dihydroguanosine

✍ Khiem V. Nguyen; James G. Muller; Cynthia J. Burrows 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 452 KB

Uric acid, a cellular antioxidant, undergoes oxidation in the presence of one-electron oxidants as well as singlet oxygen. In the present work, the oxidation pathways and products formed from oxidation of the uric acid nucleoside are compared to the more commonly studied uric acid free base. A wider