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Oxidase-Like Activity of Polymer-Coated Cerium Oxide Nanoparticles

✍ Scribed by Atul Asati; Santimukul Santra; Charalambos Kaittanis; Sudip Nath; J. Manuel Perez


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
744 KB
Volume
48
Category
Article
ISSN
0044-8249

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✦ Synopsis


Abstract

Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase‐like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB).magnified image


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