Oxidase-Like Activity of Polymer-Coated Cerium Oxide Nanoparticles
✍ Scribed by Atul Asati; Santimukul Santra; Charalambos Kaittanis; Sudip Nath; J. Manuel Perez
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 744 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0044-8249
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✦ Synopsis
Abstract
Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase‐like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB).magnified image
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