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Oxidant-induced DNA damage by quartz in alveolar epithelial cells

✍ Scribed by Roel P.F. Schins; Ad M. Knaapen; Gonca D. Cakmak; Tingming Shi; Christel Weishaupt; Paul J.A. Borm


Book ID
117766924
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
196 KB
Volume
517
Category
Article
ISSN
1383-5718

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Type II epithelial cells, which line the alveolar surface of the lung, are exposed to a variety of potentially mutagenic and carcinogenic insults. The purpose of this study was to determine if type II cells are susceptible to oxidative DNA damage in vitro. Treatment of cultured rat type II lung epit