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Oxaliplatin Plus 5-Fluorouracil and Folinic Acid (OFF) in Gemcitabine-Pretreated Advanced Pancreatic Cancer: A Phase II Study

✍ Scribed by Hend Ahmed El-Hadaad, Hanan Ahmed Wahba

Book ID
120899076
Publisher
Springer US
Year
2013
Tongue
English
Weight
125 KB
Volume
44
Category
Article
ISSN
1941-6628

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Background. Metastatic colorectal cancer is generally incurable. The most active regimen available, 5-fluorouracil(5-FU) and folinic acid (Leucovorin), produces response rates of approximately 25% to 30%. Methyl-lomustine is a nitrosourea with modest activity against colorectal cancer. A randomized