## Abstract A regimen consisting of 5‐fluorouracil/leucovorin plus oxaliplatin (FOLFOX‐6) is widely used in France in the first‐line treatment of metastatic colorectal cancer (MCRC). The aim of our study was to demonstrate the non‐inferiority of capecitabine plus oxaliplatin (XELOX) __versus__ FOLF
✦ LIBER ✦
Oxaliplatin, fluorouracil and leucovorin (FOLFOX) as first-line chemotherapy for metastatic or recurrent colorectal cancer patients
✍ Scribed by Han, Bing ;Xu, Ruihua ;Shi, Yanxia ;Luo, Huiyan ;Xiang, Xiaojuan ;Li, Yuhong ;Zhang, Li ;Lin, Tongyu ;He, Youjian
- Book ID
- 107513108
- Publisher
- Springer-Verlag
- Year
- 2007
- Weight
- 445 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1672-7118
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## Purpose This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) was superior to that of FOLFOX-4 alone as first-line treatment for metastatic colorectal cancer. The influence of KRAS mutation sta