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Overview of rationale and clinical trials with signal transduction inhibitors in lung cancer

✍ Scribed by Carlos L Arteaga; Fadlo Khuri; Geoffrey Krystal; Said Sebti


Book ID
114481183
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
128 KB
Volume
29
Category
Article
ISSN
0093-7754

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Pathways involved in the transduction of biological signals within cells overlap with those involved in oncogenesis. Previous studies have identified a number of discrete disturbances of some elements of these pathways in human lung cancer cells, by virtue of the overexpression or the mutation of ce