✦ LIBER ✦
Overview: Industrial perspectives on existing in vivo gene mutation assays
✍ Scribed by Dr. A. P. Li; Larry D. Kier
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 250 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
✦ Synopsis
In vivo gene mutation assays are considered the most definitive for the evaluation of human health risks. Suggestions are provided here for the critical evaluation of the application of established in vivo gene mutation assays and alternative approaches in the evaluation of industrial chemicals. Objective evaluation of the assays and approaches based on sound science and practical issues will allow better application of the existing assays. Such an evaluation may also help illuminate areas of improvement, as well as help guide the development of future assays.