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Overuse of training increases mechanoreceptors in supraspinatus tendon of rats SHR

✍ Scribed by Alberto de Castro Pochini; Benno Ejnisman; Maria Teresa de Seixas Alves; Luiz Fernando Uyeda; Viviane Louise Andree Nouailhetas; Sang W. Han; Moises Cohen; Walter Manna Albertoni

Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 167 KB
Volume: 29
Category: Article
ISSN: 0736-0266
DOI: 10.1002/jor.21320

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The presence of mechanoreceptors in tendon after overuse activities can be a further step to learn about tendinopathy and overuse. Studies of tendons mechanoreceptors in rats are rare. We studied 12 isogenic spontaneous hypertensive rats (SHR), which underwent an overuse protocol consisting of an hour per daily session of treadmill running at a speed of 17 m/min, 5 times/week for 4 months. Supraspinatus tendons were evaluated with immunohistochemistry using S100 protein antibodies and histological protocol. Supraspinatus tendons at the end of 4 months of overuse protocol had a high number of media mechanoreceptors (4.3) than controls (0.6). The overexpression of S100 protein antibody in overuse activities maybe could represent a adaptative effort to tendon before the tear. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 29:1771–1774, 2011

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