𝔖 Bobbio Scriptorium
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Overproduction of C9 protein the final component of membrane attack complex in the Alzheimer's brain

✍ Scribed by Li-Bang Yang; Joseph B. Rogers; Yong Shen

Book ID
117411742
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
191 KB
Volume
21
Category
Article
ISSN
0197-4580

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Human CD59 is a small membrane-bound glycoprotein that functions as an inhibitor of the membrane-attack complex (MAC) of the complement system by binding the complement proteins C8 and C9. The crystal structure of a soluble construct of CD59 has been determined to 2.1 A resolution. When compared wit