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Overloading ion-exchange membranes as a purification step for monoclonal antibodies

✍ Scribed by Arick Brown; Jerome Bill; Timothy Tully; Asha Radhamohan; Chris Dowd


Book ID
111718340
Publisher
Portland Press
Year
2010
Tongue
English
Weight
462 KB
Volume
56
Category
Article
ISSN
0885-4513

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Weak partitioning chromatography for ani
✍ Brian D. Kelley; Scott A. Tobler; Paul Brown; Jonathan L. Coffman; Ranga Godavar πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 305 KB πŸ‘ 2 views

## Abstract Weak partitioning chromatography (WPC) is an isocratic chromatographic protein separation method performed under mobile phase conditions where a significant amount of the product protein binds to the resin, well in excess of typical flowthrough operations. The more stringent load and wa