The localization and amounts of rnyoglobin (Mb) and Mb rnRNA in ragged-red fibers (RRF) in skeletal muscle of 6 patients with rnitochondrial encephalomyopathy were examined imrnunohistochemically and by in situ hybridization. The amounts of Mb and Mb mRNA were expressed in terms of optical densities
โฆ LIBER โฆ
Overexpressions of myoglobin and antioxidant enzymes in ragged-red fibers of skeletal muscle from patients with mitochondrial encephalomyopathy
โ Scribed by Makoto Kunishige; Takao Mitsui; Masashi Akaike; Masakazu Kawajiri; Masayuki Shono; Hisaomi Kawai; Toshio Matsumoto
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 827 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0148-639X
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We report a 64-year-old man presenting with multiple symmetric lipomatosis (MSL) and mitochondrial encephalomyoneuropathy. The diagnosis of a mitochondrial cytopathy was based on the typical clinical symptoms and signs, including chronic progressive external ophthalmoplegia, hearing impairment, cere