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Overexpression of γ-aminobutyric acid transporter subtype I leads to susceptibility to kainic acid-induced seizure in transgenic mice

✍ Scribed by MA, Ying Hua; HU, Jia Hua; ZHAO, Wen Juan; FEI, Jian; YU, Yun; ZHOU, Xiao Gang; MEI, Zhen Tong; GUO, Li He

Book ID
110020432
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
363 KB
Volume
11
Category
Article
ISSN
0007-0610

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## Abstract Morphine addiction has been shown to result from neural adaptations produced by repeated drug exposure, but the mechanism is still unclear. In the present study, we found that γ‐aminobutyric acid (GABA) uptake was increased in mouse brain 120 min after, but not 20 min after, morphine (1