Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma
β Scribed by Aidong Shen; Yunqing Zhang; Huiguang Yang; Ruisheng Xu; Guowei Huang
- Book ID
- 112135902
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 221 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Osteosarcoma by nature shows aggressive pulmonary metastasis; however, the underlying molecular mechanisms remain unclear. We previously showed that Nβcadherin and cadherinβ11 (OBβcadherin), which are highly expressed in normal osteoblasts, are anomalously expressed in human osteosarcom
The mta1 gene is a recently identified novel candidate metastasis-associated gene. The deduced amino acid sequence contains an src homology-3 domain binding motif, a zinc finger motif and possible phosphorylation sites, suggesting that this gene is involved in signal transduction or regulation of ge