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Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential

โœ Scribed by Bing-Sen Zhou; Pamela Tsai; Rhonda Ker; Jeffrey Tsai; Roger Ho; Johnathan Yu; Jennifer Shih; Yun Yen


Book ID
110237913
Publisher
Springer
Year
1997
Tongue
English
Weight
566 KB
Volume
16
Category
Article
ISSN
0262-0898

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## Abstract Pancreatic cancer is the most lethal of all solid tumors partially because of its chemoresistance. Although gemcitabine is widely used as a first selected agent for the treatment of this disease despite low response rate, molecular mechanisms of gemcitabine resistance in pancreatic canc