Involvement of ribonucleotide reductase
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Shin Nakahira; Shoji Nakamori; Masanori Tsujie; Yuji Takahashi; Jiro Okami; Shin
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Article
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2007
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John Wiley and Sons
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French
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## Abstract Pancreatic cancer is the most lethal of all solid tumors partially because of its chemoresistance. Although gemcitabine is widely used as a first selected agent for the treatment of this disease despite low response rate, molecular mechanisms of gemcitabine resistance in pancreatic canc