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Overexpression of the insulin-like growth factor 1 receptor (IGF-1R) is associated with malignancy in familial pheochromocytomas and paragangliomas

✍ Scribed by Fernandez, María Celia; Martin, Ayelen; Venara, Marcela; de Luján Calcagno, María; Sansó, Gabriela; Quintana, Silvina; Chemes, Héctor E.; Barontini, Marta; Pennisi, Patricia A.

Book ID
120491130
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
196 KB
Category
Article
ISSN
0300-0664

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## Abstract WWP1, a HECT type E3 ubiquitin ligase frequently amplified and overexpressed in breast cancer, has the potential to become a useful clinical biomarker and therapeutic target in breast cancer. Here, we performed immunohistochemical staining in formalin‐fixed and paraffin‐embedded tissue