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Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy

✍ Scribed by Sigrid Hoffmann; Thomas Krause; Peter Geel; Roland Willenbrock; Ines Pagel; Yigal M. Pinto; Hendrik Buikema; Wiek H. Gilst; Carsten Lindschau; Martin Paul; Tadashi Inagami; Detlev Ganten; Hidenori Urata

Publisher
Springer
Year
2001
Tongue
English
Weight
206 KB
Volume
79
Category
Article
ISSN
0946-2716

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Angiotensin II plays a crucial role in the control of blood pressure, acting at AT 1 or AT 2 receptors, and can act as a potent vasoconstrictor of the peripheral vasculature inducing hypertrophy, hyperplasia, or both, in resistance arteries. The aim of the present study was to investigate whether th