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Overexpression of the dual-specificity MAPK phosphatase PYST2 in acute leukaemia

✍ Scribed by Orlev Levy-Nissenbaum; Orit Sagi-Assif; Pia Raanani; Abraham Avigdor; Isaac Ben-Bassat; Isaac P. Witz


Book ID
117467892
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
219 KB
Volume
199
Category
Article
ISSN
0304-3835

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Characterization of the dual-specificity
✍ Orlev Levy-Nissenbaum; Orit Sagi-Assif; Isaac P. Witz πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 418 KB

PYST2 is a member of a structurally homologous subfamily of MAP kinase phosphatases. A computer-based analysis of the PYST2 locus revealed that it harbors two alternative open reading frames promoted by two conserved promoter regions. Using Northern blot analysis and reverse transcription-polymerase